Recently I saw some unexplained LUN trespasses on an EMC VNX that is used in a vSphere 5 environment where we use VAAI.
Since we use pools on the VNX, it is advised to keep a LUN on the owning SP, to prevent unnecessary traffic over the internal bus between SPA and SPB. EMC says:
Avoid trespassing pool LUNs. Trespassing the pool LUNs to another SP may adversely affect performance. After a pool LUN trespass, a pool LUNs private information remains under control of the original owning SP. This will cause the trespassed LUNs I/Os to continue to be handled by the original owning SP. When this happens both SPs being used in handling the I/Os. Involving both SPs in an I/O increases the time used to complete an I/O. Continue reading